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Other medicines that can cause breast pain include those used to treat high blood pressure and some antibiotics. Breast pain may be associated with certain antidepressants, including selective serotonin reuptake inhibitor (SSRI) antidepressants. Breast tenderness is a possible side effect of estrogen and progesterone hormone therapies that are used after menopause. Certain hormonal medications, including some infertility treatments and oral birth control pills, may be associated with breast pain. An imbalance of fatty acids within the cells may affect the sensitivity of breast tissue to circulating hormones. Breast pain associated with breast surgery and scar formation can sometimes linger after incisions have healed. Neck, shoulder and back pain may accompany breast pain that's caused by large breasts. People who have large breasts may experience noncyclic breast pain related to the size of their breasts. Other factors that may increase the risk of breast pain include: Breast pain can also occur in men who have gynecomastia, and in transgender people who are undergoing gender reassignment. Risk factorsД«reast pain is more common among people who haven't completed menopause, although it may occur after menopause. Sometimes, it's not possible to identify the exact cause of breast pain, but some factors may increase the risk. Noncyclic breast pain may be caused by trauma, prior breast surgery or other factors. These changes in the ducts and glands can cause breast cysts, which can be painful and are a common cause of cyclic breast pain. Request an Appointment at Mayo Clinic CausesД¬hanging hormone levels can cause changes in the milk ducts or milk glands.

Occurs in one specific area of your breastД«reast cancer risk is very low in people whose main symptom is breast pain, but if your doctor recommends an evaluation, it's important to follow through.

Continues daily for more than a couple of weeks.

Make an appointment with your doctor if breast pain: Arthritis that involves the cartilage in the chest, also known as costochondritis, can also cause pain.

Pulling a muscle in the chest, for example, can cause pain in the chest wall or rib cage that spreads (radiates) to the breast. The term 'extramammary' means 'outside the breast.' Extramammary breast pain feels like it starts in the breast tissue, but its source is actually outside the breast area.

In women, most likely to occur after menopause.

Usually affects one breast, in a localized area, but may spread more diffusely across the breast.

Described as tight, burning, stabbing or aching sensation.

More likely to affect people in their 20s and 30s, as well as people in their 40s who are transitioning to menopause.

Intensifies during the two weeks leading up to the start of the menstrual period, then eases up afterward.

Usually affects both breasts, particularly the upper, outer portions, and can radiate to the underarm.

Often accompanied by breast swelling, fullness or lumpiness.

Clearly related to the menstrual cycle and changing hormone levels.

Breast pain characteristics Cyclic breast pain Each type of breast pain has distinct characteristics. Noncyclic means that the pain is constant, or that there's not a regular pattern. Cyclic means that the pain occurs on a regular pattern. Unexplained breast pain that doesn't go away after one or two menstrual cycles, or that persists after menopause, or breast pain that doesn't seem to be related to hormone changes needs to be evaluated.Д«reast pain can be cyclic or noncyclic. Most times, breast pain signals a noncancerous (benign) breast condition and rarely indicates breast cancer. In transgender men, breast pain may be caused by the minimal amount of breast tissue that may remain after a mastectomy. In transgender women, hormone therapy may cause breast pain. Gynecomastia can affect one or both breasts, sometimes unevenly. This refers to an increase in the amount of breast gland tissue that's caused by an imbalance of the hormones estrogen and testosterone. In men, breast pain is most commonly caused by a condition called 'gynecomastia' (guy-nuh-koh-MAS-tee-uh).

Throughout the month, not related to a menstrual cycle.

The pain may be moderate or severe, and affects both breasts.

A week or longer each month, starting before a period and sometimes continuing through the menstrual cycle.

This normal, mild-to-moderate pain affects both breasts.

Just a few days a month, in the two to three days leading up to a menstrual period.

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